Ammonia → HCID 18915530、化合物

HRID 1292543ノート

反応式

HRID 1292543 の反応式
[NH3:1].[Cl:2][C:3]1[CH:10]=[CH:9][CH:8]=[CH:7][C:4]=1[CH:5]=O.CS(O[CH2:16][C:17]#[CH:18])(=O)=O>C1(C)C=CC=CC=1>[Cl:2][C:3]1[CH:10]=[CH:9][CH:8]=[CH:7][C:4]=1[CH:5]=[N:1][CH2:16][C:17]#[CH:18]

参加物

5

反応物 3

HCID 222AmmoniaHCID 69962-ChlorobenzaldehydeHCID 305925propargyl mesylate

生成物 1

HCID 18915530HCID 18915530、化合物

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

An aqueous 28% ammonia solution (12.1 g, 200 mmol) and o-chlorobenzaldehyde (3.65 g, 26 mmol) were mixed and a solution prepared by dissolving propargyl methanesulfonate (2.68 g, 20 mmol) in 10.7 g of toluene was added dropwise at 20° C. over 0.6 hour to the solution, followed by stirring at the same temperature for 10 hours. After separating, the resulting organic phase was concentrated to obtain a crude product of N-(2-chlorobenzylidene)-2-propynylamine.

後処理

  1. customa solution prepared
  2. additionwas added dropwise at 20° C. over 0.6 hour to the solution
  3. customAfter separating
  4. concentrationthe resulting organic phase was concentrated

出典と根拠

ORDレコード
ord-84f2fd91d93e402d9e2b917ef9edb5a1
出典データセット
uspto-grants-1998_05
特許番号
US05756769

反応ノート

読み込み中…