6-Heptynoic acid → 1-(Pent-4-ynyl)-4-propyl-3-trifluoromethyl-2,6,7-trioxabicyclo[2.2.2]octane

反応式

C(O)(=O)CCCCC#C.OC(C1(CCC)COC1)C(F)(F)F.[CH2:23]([C:29]12[O:36][CH2:35][C:32]([CH2:37][CH2:38][CH3:39])([CH2:33][O:34]1)[CH:31]([C:40]([F:43])([F:42])[F:41])[O:30]2)[CH2:24][CH2:25][CH2:26][C:27]#C>>[CH2:23]([C:29]12[O:36][CH2:35][C:32]([CH2:37][CH2:38][CH3:39])([CH2:33][O:34]1)[CH:31]([C:40]([F:41])([F:42])[F:43])[O:30]2)[CH2:24][CH2:25][C:26]#[CH:27]

参加物

反応物 3

HCID 43779506-Heptynoic acid

HCID 150219493-(1-Hydroxy-2,2,2-trifluoroethyl)-3-n-propyloxetane

HCID 193733951-(Hex-5-ynyl)-4-propyl-3-trifluoromethyl-2,6,7-trioxabicyclo[2.2.2]octane

生成物 1

HCID 193732701-(Pent-4-ynyl)-4-propyl-3-trifluoromethyl-2,6,7-trioxabicyclo[2.2.2]octane

実験手順

In an analogous manner the following compound was prepared from hept-6-ynoic acid and 3-(1-hydroxy-2,2,2-trifluoroethyl)-3-n-propyloxetane: 1-(Hex-5-ynyl)-4-propyl-3-trifluoromethyl-2,6,7-trioxabicyclo[2.2.2]octane.

出典と根拠

ORDレコード: ord-eff49d0a12214667a7d76fbee3c5cea4
出典データセット: uspto-grants-1995_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05466710

反応ノート

読み込み中…

参加物