Azane;hydrate → O-(4-cyano-2-ethoxybenzyloxy)hydroxyamine
反応式
Cl.[C:2]([C:4]1[CH:12]=[CH:11][C:7]([CH2:8][O:9]N)=[C:6]([O:13][CH2:14][CH3:15])[CH:5]=1)#[N:3].[OH2:16].[NH3:17]>>[C:2]([C:4]1[CH:12]=[CH:11][C:7]([CH2:8][O:9][O:16][NH2:17])=[C:6]([O:13][CH2:14][CH3:15])[CH:5]=1)#[N:3]参加物
3
実験手順
The O-(4-cyano-2-ethoxybenzyl)hydroxyamine hydrochloride (19) and ammonia water were mixed, then, extracted with ethyl acetate to obtain O-(4-cyano-2-ethoxybenzyl)hydroxyamine (18) (80 mg, 0.42 mmol). This was dissolved in acetonitrile (12 ml), then, several drops of 85% phosphoric acid aqueous solution were dropped on this, and the produced white solid was filtrated by filtration under reduced pressure. The filtrated substance was washed with acetonitrile, then, the filtrated substance was recovered and dried by a vacuum pump to obtain 60 mg of a while solid.
後処理
- extractionextracted with ethyl acetate
出典と根拠
- ORDレコード
- ord-b8ac6282859a4fbf923ef2bb1378f113
- 出典データセット
- uspto-grants-2007_07
- 特許番号
- US07241625B2
反応ノート
読み込み中…