3,5-Difluoropyridine → 3-[1-(5-Fluoro-pyridin-3-yl)-2-methyl-1H-imidazol-4-ylethynyl]-benzonitrile
反応式
[CH3:1][C:2]1[NH:3][CH:4]=[C:5]([C:7]#[C:8][C:9]2[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=2)[C:12]#[N:13])[N:6]=1.[F:17][C:18]1[CH:19]=[N:20][CH:21]=[C:22](F)[CH:23]=1>>[F:17][C:18]1[CH:23]=[C:22]([N:3]2[CH:4]=[C:5]([C:7]#[C:8][C:9]3[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=3)[C:12]#[N:13])[N:6]=[C:2]2[CH3:1])[CH:21]=[N:20][CH:19]=1参加物
3
実験手順
The title compound, MS: m/e=303.5 (M+), was prepared in accordance with the general method of example 1 from 3-(2-methyl-1H-imidazol-4-ylethynyl)-benzonitrile and 3,5-difluoro-pyridine.
出典と根拠
- ORDレコード
- ord-3323023331a24b949037984d765f5e98
- 出典データセット
- uspto-grants-2007_07
- 特許番号
- US07241760B2
反応ノート
読み込み中…