Hydrochloric Acid → HCID 69411345、化合物

反応式

[C:1]1([CH:7]([CH3:11])[CH2:8][C:9]#[N:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[ClH:12].[CH2:13]([OH:15])[CH3:14]>>[ClH:12].[C:1]1([CH:7]([CH3:11])[CH2:8][C:9](=[NH:10])[O:15][CH2:13][CH3:14])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

参加物

反応物 3

HCID 313Hydrochloric Acid

HCID 702Ethanol

HCID 11263561Benzenepropanenitrile, b-methyl-

生成物 1

HCID 69411345HCID 69411345、化合物

実験手順

Through a stirred solution of Example 52A (3.9 g, 26.8 mmol) in absolute ethanol (30 mL) was bubbled with hydrogen chloride gas for 20 min. The mixture was allowed to stand for overnight in the refrigerator. The product was precipitated with anhydrous ether and filtered to obtain 4.8 g of the title compound. MS (ESI/NH3) m/Z 192 (M+H)+.