2,4,6-Trihydroxybenzaldehyde → HCID 136380446、化合物

HRID 1294720ノート

反応式

HRID 1294720 の反応式
[C:1]1([NH:11][C:12](=[S:15])[NH:13][NH2:14])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.[OH:16][C:17]1[CH:24]=[C:23]([OH:25])[CH:22]=[C:21]([OH:26])[C:18]=1[CH:19]=O>C(O)(=O)C>[C:1]1([NH:11][C:12](=[S:15])[NH:13][N:14]=[CH:19][C:18]2[C:17]([OH:16])=[CH:24][C:23]([OH:25])=[CH:22][C:21]=2[OH:26])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1

参加物

4

反応物 2

HCID 680992,4,6-TrihydroxybenzaldehydeHCID 2760175N-(Naphthalen-1-yl)hydrazinecarbothioamide

生成物 1

HCID 136380446HCID 136380446、化合物収率 54%

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

実験手順

A solution of 4-(naphth-1-yl)thiosemicarbazide (572 mg, 2.63 mmol) and 2,4,6-trihydroxybenzaldehyde (405 mg, 2.63 mmol) in acetic acid (5 mL) was heated under reflux for 20 min, then cooled. The precipitate was filtered, washed (acetic acid) and dried to give the title compound (445 mg, 54%) as a solid. MS (ES+) m/e 354 [M+H]+.

後処理

  1. temperatureunder reflux for 20 min
  2. temperaturecooled
  3. filtrationThe precipitate was filtered
  4. washwashed (acetic acid)
  5. customdried

出典と根拠

ORDレコード
ord-5d878955377d46e0b30124adea33c3aa
出典データセット
uspto-grants-2007_07
特許番号
US07241783B2

反応ノート

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