Cyclohexylhydrazine hydrochloride → 1-cyclohexyl-7-fluoro-3-(4-methoxyphenyl)-1H-indazole
反応式
F[C:2]1[C:7]([F:8])=[CH:6][CH:5]=[CH:4][C:3]=1[C:9]([C:11]1[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=1)=O.Cl.[CH:20]1([NH:26][NH2:27])[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]1>CN(C1C=CN=CC=1)C>[CH:20]1([N:26]2[C:2]3[C:3](=[CH:4][CH:5]=[CH:6][C:7]=3[F:8])[C:9]([C:11]3[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=3)=[N:27]2)[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]1参加物
4
実験手順
Prepared according to Method C step A (2,3-difluorophenyl)-(4-methoxyphenyl)-methanone (0.150 g, 0.6 mmol), cyclohexylhydrazine hydrochloride (0.90 g, 0.6 mmol) and DMAP (0.073 g, 0.6 mmol) to give 0.09 g of the title compound.