Hydrogen Peroxide → HCID 69508634、化合物

HRID 1295738ノート

反応式

HRID 1295738 の反応式
[CH3:1][NH:2][CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][CH2:11][S:12][CH3:13])[CH:5]=1.[OH:14]O>C(O)(=O)C.C(Cl)Cl.C([O-])([O-])=O.[K+].[K+]>[CH3:13][S:12]([CH2:11][O:10][C:6]1[CH:5]=[C:4]([CH:9]=[CH:8][CH:7]=1)[CH2:3][NH:2][CH3:1])=[O:14]

参加物

6

反応物 2

HCID 784Hydrogen PeroxideHCID 69507792HCID 69507792、化合物

生成物 1

HCID 69508634HCID 69508634、化合物

試薬・触媒・溶媒 3

HCID 176Acetic Acid溶媒HCID 6344Dichloromethane溶媒HCID 11430Potassium Carbonate溶媒

反応条件

温度
0 °C

実験手順

Compound from step 3 (592 mg, 3.00 mmol) was dissolved in glacial acetic acid (4 mL) and cooled to 0° C. H2O2 (0.34 mL, 3.00 mmol) was added drop-wise. The mixture was allowed to stir for 6 h. The mixture was then diluted with CH2Cl2 and neutralized with K2CO3. The solids were filtered off. The filtrate was dried over Na2SO4 and concentrated in vacuo to give 640 mg (quant) of a yellow crystalline solid.

後処理

  1. filtrationThe solids were filtered off
  2. dry with materialThe filtrate was dried over Na2SO4
  3. concentrationconcentrated in vacuo
  4. customto give 640 mg (quant) of a yellow crystalline solid

出典と根拠

ORDレコード
ord-b63a465c593a4d1fa77a5b9350631b67
出典データセット
uspto-grants-2007_07
特許番号
US07244738B2

反応ノート

読み込み中…