関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 8-Aminooctanoic acid | HCID 66085 | — |
| 生成物 | Methyl 8-aminooctanoate hydrochloride | HCID 12878164 | — |
反応手順
0.7 cm3 of thionyl chloride is added to a solution of 1 g of 8-aminooctanoic acid in 40 cm3 of methanol at a temperature in the region of -20° C. and stirring is maintained for 12 hours at a temperature in the region of 20° C. The solvent is removed under reduced pressure (2.7 kPa) at a temperature in the region of 35° C. 1.48 g of methyl 8-aminooctanoate hydrochloride is thus obtained in the form of a white solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05468888 |
|---|
| 出典データセット | uspto-grants-1995_11 |
|---|
| ORD ID | ord-678f33cd827b41fe9bb0c6f946066656 |
|---|
| 出典メモ | uspto-grants-1995_11 |
|---|
