Triethylamine → 7-methoxy-4H-1,2,4-benzothiadiazine 1,1-dioxide
反応式
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH3:9])=[CH:4][C:3]=1[S:10]([NH2:13])(=[O:12])=[O:11].Cl.[CH:15](N)=N.C(N(CC)CC)C>C1(C)C=CC=CC=1>[CH3:9][O:8][C:5]1[CH:6]=[CH:7][C:2]2[NH:1][CH:15]=[N:13][S:10](=[O:11])(=[O:12])[C:3]=2[CH:4]=1参加物
5
実験手順
A suspension of 3.0 g of 2-amino-5-methoxy-benzenesulphonamide is stirred for 1 night at 80° C. in the presence of 1.31 g of formamidine hydrochloride and 2.27 ml of triethylamine in 50 ml of toluene. The toluene is evaporated off in vacuo. The residue is taken up in water and the precipitate is filtered off.
後処理
- customThe toluene is evaporated off in vacuo
- filtrationthe precipitate is filtered off
出典と根拠
- ORDレコード
- ord-f5d30bfff6d74d95a7625a7a8922fcdd
- 出典データセット
- uspto-grants-2007_07
- 特許番号
- US07250411B2
反応ノート
読み込み中…