L-(+)-Cysteine → HCID 14881543、化合物

HRID 129725

反応式

HRID 129725 の反応式
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[C:3]([CH:11]=O)[CH:2]=1.[NH2:13][C@H:14]([C:17]([OH:19])=[O:18])[CH2:15][SH:16]>C(O)C>[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[C:3]([CH:11]2[NH:13][CH:14]([C:17]([OH:19])=[O:18])[CH2:15][S:16]2)[CH:2]=1

参加物

4

反応物 2

HCID 5862L-(+)-CysteineHCID 836413-Quinolinecarboxaldehyde

生成物 1

HCID 14881543HCID 14881543、化合物収率 75%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

Quinoline-3-carbaldehyde (1.57 g) and 1.21 g of L-cysteine were dissolved in 50 ml of 50% ethanol, and the solution was stirred at room temperature for 1 hour. The resultant crystalline precipitate was collected by suction filtrating, washed with 50% ethanol and dried to give 1.95 g of 2-(3-quinolyl)thiazolidine-4-carboxylic acid. Melting point 173°-175° C. (decomposition).

後処理

  1. customThe resultant crystalline precipitate was collected by suction
  2. filtrationfiltrating
  3. washwashed with 50% ethanol
  4. customdried

出典と根拠

ORDレコード
ord-57fd1430ce8949a6a7d3214a55e2af97
出典データセット
uspto-grants-1995_11
特許番号
US05470851

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