L-(+)-Cysteine → HCID 14881540、化合物

HRID 129727

反応式

HRID 129727 の反応式
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=1)=O.[NH2:15][C@H:16]([C:19]([OH:21])=[O:20])[CH2:17][SH:18]>C(O)C>[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=2)[NH:15][CH:16]([C:19]([OH:21])=[O:20])[CH2:17][S:18]1

参加物

4

反応物 2

HCID 5862L-(+)-CysteineHCID 88065Bis(2-pyridyl) ketone

生成物 1

HCID 14881540HCID 14881540、化合物収率 11%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A mixture of 3.68 g of di-2-pyridyl ketone, 2.42 g of L-cysteine, 25 ml of ethanol was refluxed for 3.5 hours. After allowing the mixture to cool, the insoluble matter was filtered off, and the filtrate was concentrated to dryness under reduced pressure. The residue was washed in sequence with ethyl acetate and ether to give 0.63 g of 2,2-di(2-pyridyl)-thiazolidine-4-carboxylic acid.

後処理

  1. temperaturewas refluxed for 3.5 hours
  2. temperatureto cool
  3. filtrationthe insoluble matter was filtered off
  4. concentrationthe filtrate was concentrated to dryness under reduced pressure
  5. washThe residue was washed in sequence with ethyl acetate and ether

出典と根拠

ORDレコード
ord-fbee9d5e5b41400f9f3691bf051546d4
出典データセット
uspto-grants-1995_11
特許番号
US05470851

関連ノート

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