L-(+)-Cysteine → 2,2-Di(2-pyridyl)thiazolidine-4-carboxylic acid
反応式
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=1)=O.[NH2:15][C@H:16]([C:19]([OH:21])=[O:20])[CH2:17][SH:18]>C(O)C>[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=2)[NH:15][CH:16]([C:19]([OH:21])=[O:20])[CH2:17][S:18]1参加物
4
実験手順
A mixture of 3.68 g of di-2-pyridyl ketone, 2.42 g of L-cysteine, 25 ml of ethanol was refluxed for 3.5 hours. After allowing the mixture to cool, the insoluble matter was filtered off, and the filtrate was concentrated to dryness under reduced pressure. The residue was washed in sequence with ethyl acetate and ether to give 0.63 g of 2,2-di(2-pyridyl)-thiazolidine-4-carboxylic acid.
後処理
- temperaturewas refluxed for 3.5 hours
- temperatureto cool
- filtrationthe insoluble matter was filtered off
- concentrationthe filtrate was concentrated to dryness under reduced pressure
- washThe residue was washed in sequence with ethyl acetate and ether
出典と根拠
- ORDレコード
- ord-fbee9d5e5b41400f9f3691bf051546d4
- 出典データセット
- uspto-grants-1995_11
- 特許番号
- US05470851
反応ノート
読み込み中…