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Hexahydro-1,4-diazepine → 1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-[1,4]diazepane
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hexahydro-1,4-diazepine | HCID 68163 | — |
| 反応物 | 1-[Bis(4-fluorophenyl)methoxy]-2-chloroethane | HCID 10779302 | — |
| 生成物 | 1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-[1,4]diazepane | HCID 10617573 | 88% |
反応手順
Following a procedure similar to that described in Preparation 1, but using 2-[bis(4-fluorophenyl)methoxy]ethyl chloride and homopiperazine, the title compound was obtained in a yield of 88%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05470851 |
| 出典データセット | uspto-grants-1995_11 |
| ORD ID | ord-1904ea0342004963a8abe8e3efd216a2 |
| 出典メモ | uspto-grants-1995_11 |