化工社化工社 化学情報印刷レポート · 研究参考用
1,3-dimethyl-1H-indole-2-carbaldehyde → 6-fluoro-1-methyl-3-(methylaminomethyl)-1H-indole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,3-dimethyl-1H-indole-2-carbaldehyde | HCID 2771468 | — |
| 反応物 | 6-Fluoro-1-methyl-1H-indole-3-carbaldehyde | HCID 6498197 | — |
| 反応物 | Methyl 2-((5-bromopyridin-2-yl)amino)acetate | HCID 22139049 | — |
| 生成物 | 6-fluoro-1-methyl-3-(methylaminomethyl)-1H-indole | HCID 22139158 | 35% |
反応手順
According to the procedure of Preparation 11 (c), except substituting 6-fluoro-1-methyl-1H-indole-3-carboxaldehyde (0.3 g, 1.69 mmole) for the 1,3-dimethyl-1H-indole-2-carboxaldehyde, the title compound (0.11 g, 35%) was prepared as a viscous oil: MS (ES) m/e 193 (M+H)+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07250424B2 |
| 出典データセット | uspto-grants-2007_07 |
| ORD ID | ord-3338c184a94b421cae4ec52d1e6d5eac |
| 出典メモ | uspto-grants-2007_07 |