化工社化工社 化学情報印刷レポート · 研究参考用
Ethyl indole-2-carboxylate → 5-fluoro-1-methyl-1H-indole-3-carbaldehyde
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl indole-2-carboxylate | HCID 73125 | — |
| 反応物 | 5-fluoro-1H-indole-3-carbaldehyde | HCID 259089 | — |
| 生成物 | 5-fluoro-1-methyl-1H-indole-3-carbaldehyde | HCID 1382009 | 50% |
反応手順
According to the procedure of Preparation 9 (a), except substituting 5-fluoro-1H-indole-3-carboxaldehyde (0.3 g, 1.8 mmole) for the ethyl indole-2-carboxylate, the title compound (0.16 g, 50%) was prepared as a viscous oil: MS (ES) m/e 178 (M+H)+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07250424B2 |
| 出典データセット | uspto-grants-2007_07 |
| ORD ID | ord-00460c95be714cef8aaa04b42bf839c6 |
| 出典メモ | uspto-grants-2007_07 |