1,3-dimethyl-1H-indole-2-carbaldehyde → HCID 22139134、化合物

反応式

[CH3:1][O:2][C:3]1[CH:4]=[CH:5][CH:6]=[C:7]2[C:11]=1[N:10]([CH3:12])[CH:9]=[C:8]2[CH:13]=O.[CH3:15][N:16]1C2C(=CC=CC=2)C(C)=C1C=O>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][CH:6]=[C:7]2[C:11]=1[N:10]([CH3:12])[CH:9]=[C:8]2[CH2:13][NH:16][CH3:15]

参加物

反応物 2

HCID 27714681,3-dimethyl-1H-indole-2-carbaldehyde

HCID 221390927-methoxy-1-methyl-1H-indole-3-carboxaldehyde

生成物 1

HCID 22139134HCID 22139134、化合物収率 94%

実験手順

According to the procedure of Preparation 13(c), except substituting 7-methoxy-1-methyl-1H-indole-3-carboxaldehyde for the 1,3-dimethyl-1H-indole-2-carboxaldehyde, the title compound (1.6 g, 94%) was obtained as an amber oil: MS (ES) m/e 205.2 (M+H)+.

出典と根拠

ORDレコード: ord-200d7c4066b94381a1a038dbe244c4c9
出典データセット: uspto-grants-2007_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07250424B2

反応ノート

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