5-chloro-1-methyl-1H-indole-3-carbaldehyde → 5-chloro-1-methyl-3-(methylaminomethyl)-1H-indole

HRID 1297411

反応式

HRID 1297411 の反応式
BrC1C=C[C:5](NCC(OC)=O)=[N:6]C=1.[Cl:14][C:15]1[CH:16]=[C:17]2[C:21](=[CH:22][CH:23]=1)[N:20]([CH3:24])[CH:19]=[C:18]2[CH:25]=O>>[Cl:14][C:15]1[CH:16]=[C:17]2[C:21](=[CH:22][CH:23]=1)[N:20]([CH3:24])[CH:19]=[C:18]2[CH2:25][NH:6][CH3:5]

参加物

3

反応物 2

HCID 167237965-chloro-1-methyl-1H-indole-3-carbaldehydeHCID 22139049Methyl 2-((5-bromopyridin-2-yl)amino)acetate

生成物 1

HCID 221390175-chloro-1-methyl-3-(methylaminomethyl)-1H-indole収率 93%

実験手順

According to the procedure of Preparation 13 (c), except substituting 5-chloro-1-methyl-1H-indole-3-carboxaldehyde for the, 3-dimethyl-1H-indole-2-carboxaldehyde, the title compound (2.1 g, 93%) was obtained as an amber oil: MS (ES) m/e 209.0 (M+H)+.

出典と根拠

ORDレコード
ord-c2efbca3098446fe9b92a67519adf969
出典データセット
uspto-grants-2007_07
特許番号
US07250424B2

関連ノート

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