関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrogen Bromide | HCID 260 | — |
| 反応物 | Bromine | HCID 24408 | — |
| 反応物 | 4-Fluoro-2-nitroaniline | HCID 67769 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 2-Bromo-4-fluoro-6-nitroaniline | HCID 292004 | — |
反応手順
Mix 4-fluoro-2-nitroaniline (15.6 g, 0.1 mol) in water (400 mL) and add 48% hydrobromic acid (1kg). Add bromine (16 g, 0.1 mol) with stirring and stir for 1 hour. Dilute to 2L and cool to 7° C. Filter, wash with water and dry to give 4-fluoro-2-bromo-6-nitroaniline.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05470870 |
|---|
| 出典データセット | uspto-grants-1995_11 |
|---|
| ORD ID | ord-aa8ecdb05e154ce489facf8685c73331 |
|---|
| 出典メモ | uspto-grants-1995_11 |
|---|
