1,3-dimethyl-4,5,6,7-tetrahydro-1H-indene → Lithium 1,3-dimethyl-4,5,6,7-tetrahydro-1H-inden-1-ide

HRID 129983ノート

反応式

HRID 129983 の反応式
[CH3:1][C:2]1[C:3]2[CH2:4][CH2:5][CH2:6][CH2:7][C:8]=2[CH:9]([CH3:11])[CH:10]=1.[Li:12]CCCC>CCCCC>[CH3:1][C-:2]1[C:3]2[CH2:4][CH2:5][CH2:6][CH2:7][C:8]=2[C:9]([CH3:11])=[CH:10]1.[Li+:12]

参加物

4

反応物 2

HCID 129801691,3-dimethyl-4,5,6,7-tetrahydro-1H-indeneHCID 178418339Butyllithium

生成物 1

HCID 23721395Lithium 1,3-dimethyl-4,5,6,7-tetrahydro-1H-inden-1-ide収率 97%

試薬・触媒・溶媒 1

HCID 8003Pentane溶媒

実験手順

7,9 dimethylbicyclo-[4.3.0]-nona-1(6),7-diene (5.0 g, 33.5 mmol) was added to 100 mL of pentane. To this solution nBuLi (2.7M, 13 mL) was added dropwise, and the mixture was stirred for 12 hours. The resulting white precipitate was collected via filtration, washed with pentane and dried under reduced pressure to give 5.02 g (97 percent) of product.

後処理

  1. filtrationThe resulting white precipitate was collected via filtration
  2. washwashed with pentane
  3. customdried under reduced pressure

出典と根拠

ORDレコード
ord-dcdf309000d9440f88acc07b8ccba5ab
出典データセット
uspto-grants-1995_11
特許番号
US05470993

反応ノート

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