Cyanoacetamide → 2-Cyano-2-cyclohexylidene-acetamide
反応式
[C:1]1(=O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[C:8]([CH2:10][C:11]([NH2:13])=[O:12])#[N:9]>>[C:1]1(=[C:10]([C:8]#[N:9])[C:11]([NH2:13])=[O:12])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1参加物
3
実験手順
Reaction 1. consists of condensing the cyclohexanone (I) with cyanoacetamide, to obtain 2-cyclohexylidene-2-cyanoacetamide (IX); this reaction can be undertaken for example in toluene, in the presence of ammonium acetate and acetic acid, heating to a temperature between 20 and 150° C., and preferably to the reflux temperature of the reaction mixture; the compound IX is separated from the reaction mixture.
後処理
- customReaction 1
出典と根拠
- ORDレコード
- ord-4850e2d858e9406fbd9625fdcdfcc579
- 出典データセット
- uspto-grants-2008_06
- 特許番号
- US07381823B2
反応ノート
読み込み中…