化工社化工社 化学情報印刷レポート · 研究参考用
Ammonia → 5-iodo-6-methyl-1H-indazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ammonia | HCID 222 | — |
| 反応物 | 1-Acetyl-5-iodo-6-methylindazole | HCID 59339735 | — |
| 溶媒 | MeOH tetrahydrofuran | HCID 21899815 | — |
| 生成物 | 5-iodo-6-methyl-1H-indazole | HCID 59339696 | 100.8% |
反応手順
1-Acetyl-5-iodo-6-methylindazole (1.5 g, 5.0 mmol) was stirred with ammonia (7 M in methanol, 4 mL) in methanol/THF (2/1, 15 mL) for 1 h. The solution was evaporated to give the subtitle compound (1.3 g, 100%) as an off-white powder.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07728030B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-a3777dfc9212454d95566e05647ea08e |
| 出典メモ | uspto-grants-2010_06 |