3-Phenoxy-1,2-propanediol → Phenoxyacetaldehyde

HRID 13077

反応式

HRID 13077 の反応式
I([O-])(=O)(=O)=O.[Na+].[O:7]([CH2:14][CH:15]([OH:18])CO)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>ClCCl>[O:7]([CH2:14][CH:15]=[O:18])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

参加物

4

反応物 2

HCID 108573-Phenoxy-1,2-propanediolHCID 23667635Sodium periodate

生成物 1

HCID 75033Phenoxyacetaldehyde収率 100%

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒2 回

実験手順

Sodium periodate (0.65 M in water, 20 mL) was added to a vigorously stirred suspension of silica gel (20 g) in dichloromethane (160 mL), followed by a solution of 3-phenoxy-1,2-propanediol (1.68 g, 10.0 mmol) in dichloromethane (20 mL). After stirring for 10 min the mixture was filtered and the filtrate was concentrated to give the subtitle compound (1.36 g, 100%).

後処理

  1. filtrationwas filtered
  2. concentrationthe filtrate was concentrated

出典と根拠

ORDレコード
ord-1e1e15121926420891672153556960f2
出典データセット
uspto-grants-2010_06
特許番号
US07728030B2

関連ノート

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