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Hydrochloric Acid → PD-117596 hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | 1-Cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | HCID 535414 | — |
| 反応物 | 3-(2,2-Dimethylpropylideneamino)-pyrrolidine | HCID 14836604 | — |
| 生成物 | PD-117596 hydrochloride | HCID 13590048 | — |
反応手順
If, for example, 1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid is reacted with 3-(2,2-dimethylpropylideneamino)-pyrrolidine and the reaction product is treated with hydrochloric acid, 7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid hydrochloride is obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05723627 |
| 出典データセット | uspto-grants-1998_03 |
| ORD ID | ord-269b34579b6543ad8b25187fc9fff0bb |
| 出典メモ | uspto-grants-1998_03 |