化工社化工社 化学情報印刷レポート · 研究参考用
Hydrogen Bromide → 16-Bromohexadecanoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrogen Bromide | HCID 260 | — |
| 反応物 | 16-Hydroxyhexadecanoic acid | HCID 10466 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 16-Bromohexadecanoic acid | HCID 620397 | 99% |
反応手順
16-Bromohexadecanoic acid was prepared by refluxing for 48 hrs 5.0 gr (18.35 mmole) of 16-hydroxyhexadecanoic acid in 24 ml of 1:1 v/v mixture of HBr (48% aqueous solution) and glacial acetic acid. Upon cooling, crude product was solidified inside the reaction vessel. It was filtered out and washed with 3×100 ml of cold water. 6.1 gr (99% yield) of the desired product were obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07384749B2 |
| 出典データセット | uspto-grants-2008_06 |
| ORD ID | ord-5c24e10a6f8444acbd4e7766507ebdd8 |
| 出典メモ | uspto-grants-2008_06 |