反応式
[CH:1]([C:4]1[CH:5]=[CH:6][C:7]([NH:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[N+:19]([O-])=O)=[C:8]([CH:11]=1)[C:9]#[N:10])([CH3:3])[CH3:2].[Sn](Cl)[Cl:23]>Cl.C(O)C>[ClH:23].[CH:1]([C:4]1[CH:5]=[CH:6][C:7]2[NH:12][C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=3[N:19]=[C:9]([NH2:10])[C:8]=2[CH:11]=1)([CH3:3])[CH3:2]参加物
5
反応条件
- 温度
- 86 °C
実験手順
Combine 5-isopropyl-2-(2-nitro-phenylamino)-benzonitrile (4.54 g, 16.1 mmol) and tin (II) chloride (10.92 g, 48.4 mmol) in 65.0 mL of 5N HCl solution and 65.0 mL of ethanol. Heat this mixture at 86° C. for 18 hours. Chilling the mixture precipitates the title compound as 4.22 g of a yellow solid: mp>250° C.; mass spectrum (ion spray): m/z=252 (M+1).
後処理
- temperatureChilling the mixture
- customprecipitates the title compound as 4.22 g of a yellow solid
出典と根拠
- ORDレコード
- ord-2fe6f9243a0e4cf0a9d651c057014da0
- 出典データセット
- uspto-grants-2008_06
- 特許番号
- US07384934B2
関連ノート
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