4-Hydroxybenzylamine → HCID 10200939、化合物

HRID 131683

反応式

HRID 131683 の反応式
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]([CH3:13])=[N:11][N:12]=2)=[CH:4][C:3]=1[C:14]1[CH:19]=[CH:18][C:17]([C:20](O)=[O:21])=[CH:16][CH:15]=1.[OH:23][C:24]1[CH:31]=[CH:30][C:27]([CH2:28][NH2:29])=[CH:26][CH:25]=1>>[OH:23][C:24]1[CH:31]=[CH:30][C:27]([CH2:28][NH:29][C:20]([C:17]2[CH:18]=[CH:19][C:14]([C:3]3[CH:4]=[C:5]([C:8]4[O:9][C:10]([CH3:13])=[N:11][N:12]=4)[CH:6]=[CH:1][C:2]=3[CH3:7])=[CH:15][CH:16]=2)=[O:21])=[CH:26][CH:25]=1

参加物

3

反応物 2

HCID 974724-HydroxybenzylamineHCID 112201194-[2-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]benzoic Acid

生成物 1

HCID 10200939HCID 10200939、化合物

実験手順

N-(4-Hydroxybenzyl)-2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxamide was prepared from 2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxylic acid and 4-hydroxybenzylamine using method H. NMR; δH [2H6]—DMSO 9.27,(1H, s), 9.02,(1H, t), 7.98,(2H, d), 7.89,(1H, dd), 7.76,(1H, d), 7.54,,(1H, d), 7.51,(2H, d), 7.13,(2H, d), 6.71,(2H, d), 4.39,(2H, d), 2.56,(3H, s), 2.31,(3H, s), LCMS; retention time 3.03 min, MH+ 400.

出典と根拠

ORDレコード
ord-917d1a4daf16441e8018ffb6fc38fd78
出典データセット
uspto-grants-2008_06
特許番号
US07384963B2

関連ノート

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