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2-Hydroxy-N,N-dimethylbenzamide → 5-(2-Dimethylcarbamoyl-phenoxy)-6-(4-methanesulfonyl-phenoxy)-2-pyridin-2-yl-1H-benzimidazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Hydroxy-N,N-dimethylbenzamide | HCID 74500 | — |
| 反応物 | 5-(2-Ethoxycarbonyl-phenoxy)-6-(4-methanesulfonyl-phenoxy)-2-pyridin-2-yl-1H-benzimidazole | HCID 23145140 | — |
| 生成物 | 5-(2-Dimethylcarbamoyl-phenoxy)-6-(4-methanesulfonyl-phenoxy)-2-pyridin-2-yl-1H-benzimidazole | HCID 23145352 | — |
反応手順
The entitled compound was obtained in the same method as in Example 14 or in accordance with the method or by combining it with an ordinary method but using 4-fluoro-5-(4-methanesulfonyl-phenoxy)-2-nitro-phenylamine obtained in Example 14 and 2-hydroxybenzoic acid dimethylamide in order.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07728025B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-add36451338c4ee9a2bb43c5f598956f |
| 出典メモ | uspto-grants-2010_06 |