化工社化工社 化学情報印刷レポート · 研究参考用
HRID 13292作成日：2026年10月26日
Potassium Carbonate → 5-(2-Cyano-phenoxy)-4-(6-methanesulfonyl-pyridin-3-yloxy)-2-nitro-phenylamine
https://huagongshe.com/reaction/13292
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 2-Hydroxybenzonitrile | HCID 11907 | — |
| 反応物 | N-methyl-2-pyrrolidone | HCID 13387 | — |
| 反応物 | 5-Fluoro-4-(6-methanesulfonyl-pyridin-3-yloxy)-2-nitro-phenylamine | HCID 23145333 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 5-(2-Cyano-phenoxy)-4-(6-methanesulfonyl-pyridin-3-yloxy)-2-nitro-phenylamine | HCID 23145776 | — |
反応手順
60 mg of 2-hydroxy-benzonitrile and 70 mg of potassium carbonate were added to an N-methylpyrrolidinone (2 ml) solution of 150 mg of 5-fluoro-4-(6-methanesulfonyl-pyridin-3-yloxy)-2-nitro-phenylamine obtained in (step 3), and the reaction liquid was stirred at 90° C. for 5 hours. Water was added to the reaction liquid, and the deposit was taken out through filtration to obtain the entitled compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07728025B2 |
|---|
| 出典データセット | uspto-grants-2010_06 |
|---|
| ORD ID | ord-2db017ca3f4142d080bb5cc0e86c3cf0 |
|---|
| 出典メモ | uspto-grants-2010_06 |
|---|
