Cyclopropanecarboxylic acid → HCID 10171796、化合物

反応式

[N:1]1[NH:2][C:3]2[CH:4]=[CH:5][CH:6]=[C:7]3[CH2:13][CH2:12][C:11]4=[C:14]([NH2:18])[CH:15]=[CH:16][CH:17]=[C:10]4[C:9]=1[C:8]=23.[CH:19]1([C:22](O)=[O:23])[CH2:21][CH2:20]1>>[N:1]1[NH:2][C:3]2[CH:4]=[CH:5][CH:6]=[C:7]3[CH2:13][CH2:12][C:11]4[C:14]([NH:18][C:22]([CH:19]5[CH2:21][CH2:20]5)=[O:23])=[CH:15][CH:16]=[CH:17][C:10]=4[C:9]=1[C:8]=23

参加物

反応物 2

HCID 15655Cyclopropanecarboxylic acid

HCID 10149166HCID 10149166、化合物

生成物 1

HCID 10171796HCID 10171796、化合物

実験手順

6,7-Dihydro-2H-benzo[6,7]cyclohepta[cd]indazole-8-amine prepared in Example 8 and cyclopropanecarboxylic acid were subjected to the reaction and purified and separated by LC-MS in the same manner as in Synthesis Process A, to give the title compound.

後処理

custompurified
customseparated by LC-MS in the same manner as in Synthesis Process A

出典と根拠

ORDレコード: ord-a07b5a64ab1c401c8fba6c5bba67a17e
出典データセット: uspto-grants-2008_06
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07390797B2

反応ノート

読み込み中…

参加物