(2S)-2,5-Dihydro-2-isopropyl-3,6-dimethoxypyrazine → Pyrazine, 2,5-dihydro-3,6-dimethoxy-2-(1-methylethyl)-5-[(2,4,5-trifluorophenyl)methyl]-, (2S,5R)-
反応式
[CH3:1][O:2][C:3]1[C@H:4]([CH:11]([CH3:13])[CH3:12])[N:5]=[C:6]([O:9][CH3:10])[CH2:7][N:8]=1.[F:14][C:15]1[CH:22]=[C:21]([F:23])[C:20]([F:24])=[CH:19][C:16]=1[CH2:17]Br>>[CH3:1][O:2][C:3]1[C@H:4]([CH:11]([CH3:13])[CH3:12])[N:5]=[C:6]([O:9][CH3:10])[C@@H:7]([CH2:17][C:16]2[CH:19]=[C:20]([F:24])[C:21]([F:23])=[CH:22][C:15]=2[F:14])[N:8]=1参加物
3
実験手順
The title compound (3.81 g) was prepared from 3.42 g (18.5 mmol) of (2S)-2,5-dihydro-3,6-dimethoxy-2-isopropylpyrazine and 5 g (22.3 mmol) of 2,4,5-trifluorobenzyl bromide using the procedure described for Intermediate 2, Step A.
出典と根拠
- ORDレコード
- ord-081c3007b1554c82954eae42c5c62f2c
- 出典データセット
- uspto-grants-2008_06
- 特許番号
- US07390809B2
反応ノート
読み込み中…