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Methanol → Methyl 3-Hydroxyphenylacetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | 3'-Hydroxyphenylacetic acid | HCID 12122 | — |
| 溶媒 | Sulfuric Acid | HCID 1118 | — |
| 生成物 | Methyl 3-Hydroxyphenylacetate | HCID 39129 | — |
反応手順
10 g of 3-hydroxyphenylacetic acid are dissolved in 60 ml of methanol and 2.5 ml of sulphuric acid. The solution is heated at reflux for two hours. It is brought back to ambient temperature and the methanol is evaporated. The residue is taken up in a saturated K2CO3 solution. Extraction is carried out with AcOEt. The organic phase is dried over MgSO4, filtered and evaporated to dryness. 11.1 g of oil are obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07390818B2 |
| 出典データセット | uspto-grants-2008_06 |
| ORD ID | ord-7422c6e426094c6b92808842d39c97dd |
| 出典メモ | uspto-grants-2008_06 |