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3,4-Dichloroaniline → N-(3,4-dichlorophenyl)alanine Benzyl Ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3,4-Dichloroaniline | HCID 7257 | — |
| 反応物 | Benzyl 2-oxopropanoate | HCID 11769098 | — |
| 生成物 | N-(3,4-dichlorophenyl)alanine Benzyl Ester | HCID 15434839 | — |
反応手順
Following General Procedure AA above and using 3,4-dichloroaniline (Aldrich) and benzyl pyruvate (prepared by following General Procedure AO above using benzyl alcohol in place of iso-butanol), the title compound was prepared as an oil. The reaction was monitored by tlc on silica gel (Rf=0.4 in 25% EtOAc/hexanes) and purification was by preparative plate chromatography (silica gel using 25% EtOAc/hexanes as the eluant).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07390801B2 |
| 出典データセット | uspto-grants-2008_06 |
| ORD ID | ord-53ad6f4396d240da98f23cb42cff3379 |
| 出典メモ | uspto-grants-2008_06 |