(3-Methoxyphenyl)acetic acid → 2-[(3-Methoxyphenyl)acetamido]butyric acid isobutyl ester
反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:9][C:10]([OH:12])=O)[CH:6]=[CH:7][CH:8]=1.[NH2:13][CH:14]([CH2:22][CH3:23])[C:15]([O:17][CH2:18][CH:19]([CH3:21])[CH3:20])=[O:16]>>[CH2:18]([O:17][C:15](=[O:16])[CH:14]([NH:13][C:10](=[O:12])[CH2:9][C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([O:2][CH3:1])[CH:4]=1)[CH2:22][CH3:23])[CH:19]([CH3:20])[CH3:21]参加物
3
実験手順
Following General Procedure BI above and using 3-methoxyphenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.
後処理
- customThe reaction was monitored by tlc on silica gel and purification
- filtrationwas by filtration
出典と根拠
- ORDレコード
- ord-6f2084b7b04f411aabc042629f77e910
- 出典データセット
- uspto-grants-2008_06
- 特許番号
- US07390801B2
反応ノート
読み込み中…