化工社化工社 化学情報印刷レポート · 研究参考用
2,4-Difluorobenzonitrile → 4-(2-Cyano-5-fluoro-phenoxy)-6-(6-ethanesulfonyl-pyridin-3-yloxy)-2-pyrazin-2-yl-1H-benzimidazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2,4-Difluorobenzonitrile | HCID 77545 | — |
| 反応物 | 4-(2-Cyano-6-fluoro-phenoxy)-6-(6-ethanesulfonyl-pyridin-3-yloxy)-2-pyrazin-2-yl-1H-benzimidazole | HCID 11318284 | — |
| 生成物 | 4-(2-Cyano-5-fluoro-phenoxy)-6-(6-ethanesulfonyl-pyridin-3-yloxy)-2-pyrazin-2-yl-1H-benzimidazole | HCID 23145774 | — |
反応手順
The entitled compound was obtained in the same method as in Example 438 (step 2) or in accordance with the method or by combining it with an ordinary method but using 4-hydroxy-6-(6-ethanesulfonyl-pyridin-3-yloxy)-2-pyrazin-2-yl-1H-benzimidazole obtained in Example 442 and 2,4-difluoro-benzonitrile.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07728025B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-66a93e76712942c3813a3be8630cacbb |
| 出典メモ | uspto-grants-2010_06 |