反応式
[C:1]([C:3]1[CH:36]=[CH:35][CH:34]=[C:33](F)[C:4]=1[O:5][C:6]1[C:14]2[N:13]=[C:12]([C:15]3[CH:20]=[N:19][CH:18]=[CH:17][N:16]=3)[NH:11][C:10]=2[CH:9]=[C:8]([O:21][C:22]2[CH:23]=[N:24][C:25]([S:28]([CH2:31][CH3:32])(=[O:30])=[O:29])=[CH:26][CH:27]=2)[CH:7]=1)#[N:2].[F:38]C1C=C(F)C=CC=1C#N>>[C:1]([C:3]1[CH:36]=[CH:35][C:34]([F:38])=[CH:33][C:4]=1[O:5][C:6]1[C:14]2[N:13]=[C:12]([C:15]3[CH:20]=[N:19][CH:18]=[CH:17][N:16]=3)[NH:11][C:10]=2[CH:9]=[C:8]([O:21][C:22]2[CH:23]=[N:24][C:25]([S:28]([CH2:31][CH3:32])(=[O:30])=[O:29])=[CH:26][CH:27]=2)[CH:7]=1)#[N:2]参加物
3
実験手順
The entitled compound was obtained in the same method as in Example 438 (step 2) or in accordance with the method or by combining it with an ordinary method but using 4-hydroxy-6-(6-ethanesulfonyl-pyridin-3-yloxy)-2-pyrazin-2-yl-1H-benzimidazole obtained in Example 442 and 2,4-difluoro-benzonitrile.
後処理
- customThe entitled compound was obtained in the same method as in Example 438 (step 2) or in accordance with the method
出典と根拠
- ORDレコード
- ord-66a93e76712942c3813a3be8630cacbb
- 出典データセット
- uspto-grants-2010_06
- 特許番号
- US07728025B2
関連ノート
読み込み中…