5-Bromo-2,4-difluorobenzenesulfonamide → 5-[7-Difluoromethyl-5-(3-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-2,4-difluoro-benzenesulfonamide

反応式

[Br:25][c:26]1[c:27]([F:37])[cH:28][c:29]([F:36])[c:30]([S:32](=[O:33])(=[O:34])[NH2:35])[cH:31]1.[F:1][CH:2]([c:3]1[cH:4][c:5](-[c:14]2[cH:15][c:16]([C:20]([F:21])([F:22])[F:23])[cH:17][cH:18][cH:19]2)[n:6][c:7]2[n:8]1[n:9][cH:10][c:11]2[C:12]#[CH:13])[F:24]>>[F:1][CH:2]([c:3]1[cH:4][c:5](-[c:14]2[cH:15][c:16]([C:20]([F:21])([F:22])[F:23])[cH:17][cH:18][cH:19]2)[n:6][c:7]2[n:8]1[n:9][cH:10][c:11]2[C:12]#[C:13][c:26]1[c:27]([F:37])[cH:28][c:29]([F:36])[c:30]([S:32](=[O:33])(=[O:34])[NH2:35])[cH:31]1)[F:24]

参加物

反応物 2

HCID 27732955-Bromo-2,4-difluorobenzenesulfonamide

HCID 866080813-Ethynyl-7-difluoromethyl-5-(3-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine

生成物 1

HCID 118525175-[7-Difluoromethyl-5-(3-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-2,4-difluoro-benzenesulfonamide

出典と根拠

ORDレコード: ord-dc4d19f06a854348ae1a86d3400dedfb
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…