Tert-butyl 4-{2-[(4-bromophenyl)amino]-1-methylbenzimidazol-5-yloxy}pyridine-2-carboxylate → 4-{2-[(4-Bromophenyl)amino]-1-methylbenzimidazol-5-yloxy}pyridine-2-carboxylic acid

関与物質

反応手順

A solution of the product of step 7 in trifluoroacetic acid was treated with two drops of water at room temperature for 3-4 hours or until the reaction was determined to be complete by HPLC. The reaction was evaporated under reduced pressure to afford the product as a red-orange oil in quantitative yield. MS: MH+=439.

情報源と証拠