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2-(1H-pyrrol-1-yl)aniline → (2S,4EZ)-4-[(allyloxy)imino]-1-(4-cyanobenzoyl)-N-[2-(1H-pyrrol-1-yl)phenyl]-2-pyrrolidinecarboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-(1H-pyrrol-1-yl)aniline | HCID 80123 | — |
| 反応物 | 4-Cyanobenzoyl chloride | HCID 80172 | — |
| 反応物 | (2S,4EZ)-4-[(allyloxy)imino)-1-(tert-butoxycarbonyl)-2-pyrrolidinecarboxylic acid | HCID 58714562 | — |
| 生成物 | (2S,4EZ)-4-[(allyloxy)imino]-1-(4-cyanobenzoyl)-N-[2-(1H-pyrrol-1-yl)phenyl]-2-pyrrolidinecarboxamide | HCID 131725415 | — |
反応手順
Following the general method as outlined in Example 22, starting from (2S,4EZ)-4-[(allyloxy)-imino]-1-(tert-butoxycarbonyl)-2-pyrrolidinecarboxylic acid, 4-cyanobenzoyl chloride, and 2-(1H-pyrrol-1-yl)phenylamine the title compound was obtained in 51% purity by LC/MS. MS(ESI+): m/z=454.4.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07211601B2 |
| 出典データセット | uspto-grants-2007_05 |
| ORD ID | ord-b609a776f69b4e1985ac5b7f3c265320 |
| 出典メモ | uspto-grants-2007_05 |