2-(1H-pyrrol-1-yl)aniline → (2S,4EZ)-4-(tert-butoxyimino)-N-[2-(1H-pyrrol 1-yl)phenyl]-2-pyrrolidinecarboxamide

HRID 1349050

反応式

HRID 1349050 の反応式
C(OC([N:8]1[CH2:12][C:11](=[N:13][O:14][C:15]([CH3:18])([CH3:17])[CH3:16])[CH2:10][C@H:9]1[C:19]([OH:21])=O)=O)(C)(C)C.[N:22]1([C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=2[NH2:33])[CH:26]=[CH:25][CH:24]=[CH:23]1>>[C:15]([O:14][N:13]=[C:11]1[CH2:12][NH:8][C@H:9]([C:19]([NH:33][C:28]2[CH:29]=[CH:30][CH:31]=[CH:32][C:27]=2[N:22]2[CH:26]=[CH:25][CH:24]=[CH:23]2)=[O:21])[CH2:10]1)([CH3:16])([CH3:17])[CH3:18]

参加物

3

反応物 2

HCID 801232-(1H-pyrrol-1-yl)anilineHCID 131725425(2S,4EZ)-1-(tertbutoxycarbonyl)-4-(tert-butoxyimino)-2-pyrrolidinecarboxylic acid

生成物 1

HCID 131725432(2S,4EZ)-4-(tert-butoxyimino)-N-[2-(1H-pyrrol 1-yl)phenyl]-2-pyrrolidinecarboxamide

実験手順

Following the general method as outlined in Example 22, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(tert-butoxyimino)-2-pyrrolidinecarboxylic acid, and 2-(1H-pyrrol-1-yl)phenylamine the title compound was obtained in 83% purity by LC/MS. MS(ESI+): m/z=341.2.

出典と根拠

ORDレコード
ord-d73187ef45b2482593122883bf13aa05
出典データセット
uspto-grants-2007_05
特許番号
US07211601B2

関連ノート

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