Sulfuric Acid → Diphenylmethyl acetate

HRID 1349352ノート

反応式

HRID 1349352 の反応式
[C:1](OC(=O)C)(=[O:3])[CH3:2].S(=O)(=O)(O)O.[CH:13]([OH:26])([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>ClCCl>[C:1]([O:26][CH:13]([C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)(=[O:3])[CH3:2]

参加物

5

反応物 3

HCID 1118Sulfuric AcidHCID 7037BenzhydrolHCID 7918Acetic Anhydride

生成物 1

HCID 274281Diphenylmethyl acetate

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

反応条件

温度
0 °C

実験手順

108.3 g (1.05 mol; 1.05 eq) of acetic anhydride are diluted in 370 ml of dichloromethane at 20° C. The solution obtained is cooled to 0±2° C. before introducing 2.8 ml of a 96% sulphuric acid solution in a time of about 10 minutes. After stirring for about 10 minutes, 184.2 g (1 mol, 1 eq) of benzhydrol are introduced in portions at 0° C.±2° C. in 60±15 minutes. The reaction medium is maintained in contact for 2 hours at this temperature.

後処理

  1. customThe solution obtained
  2. temperatureThe reaction medium is maintained in contact for 2 hours at this temperature

出典と根拠

ORDレコード
ord-f875a27ed09b42028c8d52fc0814385a
出典データセット
uspto-grants-2007_05
特許番号
US07211684B2

反応ノート

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