5-(2-Bromoethoxy)-2-methylquinoline → 4-Methyl-8-{1-[2-(2-methylquinolin-5-yloxy)ethyl]piperidin-4-ylmethyl}-4H-benzo[1,4]oxazin-3-one
反応式
[CH3:1][N:2]1[C:7]2[CH:8]=[CH:9][CH:10]=[C:11]([CH2:12][CH:13]3[CH2:18][CH2:17][NH:16][CH2:15][CH2:14]3)[C:6]=2[O:5][CH2:4][C:3]1=[O:19].Br[CH2:21][CH2:22][O:23][C:24]1[CH:33]=[CH:32][CH:31]=[C:30]2[C:25]=1[CH:26]=[CH:27][C:28]([CH3:34])=[N:29]2>>[CH3:1][N:2]1[C:7]2[CH:8]=[CH:9][CH:10]=[C:11]([CH2:12][CH:13]3[CH2:18][CH2:17][N:16]([CH2:21][CH2:22][O:23][C:24]4[CH:33]=[CH:32][CH:31]=[C:30]5[C:25]=4[CH:26]=[CH:27][C:28]([CH3:34])=[N:29]5)[CH2:15][CH2:14]3)[C:6]=2[O:5][CH2:4][C:3]1=[O:19]参加物
3
実験手順
The title compound was prepared from 4-methyl-8-(piperidin-4-ylmethyl)4H-benzo[1,4]oxazin-3-one and 5-(2-bromoethoxy)-2-methylquinoline in a similar manner to Example 1.
出典と根拠
- ORDレコード
- ord-b5d90462d81d4fa1b1bec110a392345b
- 出典データセット
- uspto-grants-2007_05