化工社化工社 化学情報印刷レポート · 研究参考用
Dimethylamine → N,N-dimethyl-5-nitropyridin-2-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dimethylamine | HCID 674 | — |
| 反応物 | Water | HCID 962 | — |
| 反応物 | 2-Chloro-5-nitropyridine | HCID 78308 | — |
| 溶媒 | N-methyl-2-pyrrolidone | HCID 13387 | — |
| 生成物 | N,N-dimethyl-5-nitropyridin-2-amine | HCID 75707 | — |
反応手順
2-Chloro-5-nitropyridine (1.0 eq) and dimethylamine (2 M in EtOH, 4.6 eq) in NMP were heated for 2 h at 100° C. The solution was then poured slowly into H2O. The filtrate that formed was filtered and dried to give 2-(dimethylamino)-5-nitropyridine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07728010B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-34aaa92fa23d45839859c9f55903dc35 |
| 出典メモ | uspto-grants-2010_06 |