Tert-Butylamine → 1-tert-butyl-1H-imidazole-5-carbaldehyde

反応式

Cl.C(=N)OCC.[C:7]([NH2:11])([CH3:10])([CH3:9])[CH3:8].C1(N2[C:19]([CH:20]=[O:21])=[CH:18][N:17]=[C:16]2C)CC1>>[C:7]([N:11]1[C:19]([CH:20]=[O:21])=[CH:18][N:17]=[CH:16]1)([CH3:10])([CH3:9])[CH3:8]

参加物

反応物 3

HCID 6385Tert-Butylamine

HCID 12578842Ethyl formimidate hydrochloride

HCID 210973073-cyclopropyl-2-methyl-3H-imidazole-4-carbaldehyde

生成物 1

HCID 210973151-tert-butyl-1H-imidazole-5-carbaldehyde

実験手順

3-tert-Butyl-3H-imidazole-4-carbaldehyde was prepared from ethyl formimidate hydrochloride (Aldrich) and tert-butylamine in the same manner as 3-cyclopropyl-2-methyl-3H-imidazole-4-carbaldehyde (Example 45).

出典と根拠

ORDレコード: ord-42c04b9c65444215843e2d4230708b99
出典データセット: uspto-grants-2007_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07214802B2

反応ノート

読み込み中…