3-Iodophthalic acid → 3-Iodophthalic anhydride

HRID 1351699

反応式

HRID 1351699 の反応式
[I:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:4]([C:5]([OH:7])=O)[C:3]=1[C:11]([OH:13])=[O:12]>C(OC(=O)C)(=O)C>[I:1][C:2]1[C:3]2[C:11](=[O:12])[O:13][C:5](=[O:7])[C:4]=2[CH:8]=[CH:9][CH:10]=1

参加物

3

反応物 1

HCID 2382313-Iodophthalic acid

生成物 1

HCID 2820713-Iodophthalic anhydride収率 65.2%

試薬・触媒・溶媒 1

HCID 7918Acetic Anhydride溶媒

実験手順

A solution of 3-iodophthalic acid (0.9 g, 3.08 mmol) in acetic anhydride (5 mL) was heated to reflux under nitrogen overnight. After cooling, the solvent was removed in vacuo and the residue purified by trituration with ethanol to give 4-iodo-2-benzofuran-1,3-dione (0.55 g, 65%).

後処理

  1. temperatureto reflux under nitrogen overnight
  2. temperatureAfter cooling
  3. customthe solvent was removed in vacuo
  4. customthe residue purified by trituration with ethanol

出典と根拠

ORDレコード
ord-4318fe1b7da8414a98ba2ac85f02026d
出典データセット
uspto-grants-2007_05
特許番号
US07217740B2

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