10-Methoxyibogamine → CID 44359441

HRID 1352187

反応式

HRID 1352187 の反応式
[CH3:1][CH2:2][C@@H:3]1[C@@H:8]2[N:9]3[CH2:11][CH2:12][C:13]4[C:17]5[CH:18]=[C:19]([O:22]C)[CH:20]=[CH:21][C:16]=5[NH:15][C:14]=4[C@@H:7]2[CH2:6][C@@H:5]([CH2:10]3)[CH2:4]1.B(Br)(Br)Br.C(Cl)Cl>>[CH3:1][CH2:2][C@H:3]1[CH:8]2[N:9]3[CH2:11][CH2:12][C:13]4[C:17]5[CH:18]=[C:19]([OH:22])[CH:20]=[CH:21][C:16]=5[NH:15][C:14]=4[C@H:7]2[CH2:6][CH:5]([CH2:10]3)[CH2:4]1

参加物

3

反応物 2

HCID 44210810-Methoxyibogamine2 回HCID 22277759Boron tribromide dichloromethane

生成物 1

HCID 44359441CID 44359441

実験手順

Noribogaine is synthesized by the O-demethylation of ibogaine. This may be accomplished, for example, by reacting ibogaine with boron tribromide/methylene chloride at room temperature and then purifying the product using known procedures. At present, noribogaine may also be obtained from the National Institute on Drug Abuse (Rockville, Md.). The compound has the following structure:

後処理

  1. customat room temperature
  2. custompurifying the product

出典と根拠

ORDレコード
ord-c915d17f15e7494d9314ddada26f95d1
出典データセット
uspto-grants-2007_05
特許番号
US07220737B1

関連ノート

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