(+-)-2-Butanol → 2-Sec-butoxy-5-methanesulfonyl-benzoic acid
反応式
Cl[C:2]1[CH:10]=[CH:9][C:8]([S:11]([CH3:14])(=[O:13])=[O:12])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].[CH3:15][CH:16]([OH:19])[CH2:17][CH3:18]>>[CH:16]([O:19][C:2]1[CH:10]=[CH:9][C:8]([S:11]([CH3:14])(=[O:13])=[O:12])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5])([CH2:17][CH3:18])[CH3:15]参加物
3
実験手順
Prepared in analogy to Example A1 (b) from 2-chloro-5-methanesulfonyl-benzoic acid (Example A1(a)) and rac-butan-2-ol. The crude material was purified by preparative HPLC to yield the title compound as a white solid. MS (m/e): 271.4 ([M−H]−, 100%).
後処理
- customThe crude material was purified by preparative HPLC
出典と根拠
- ORDレコード
- ord-6ec63ae73e8945939112276519955628
- 出典データセット
- uspto-grants-2007_05
- 特許番号
- US07220744B2
反応ノート
読み込み中…