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Thiophosgene → 3-Phenoxyphenylisothiocyanate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thiophosgene | HCID 10040 | — |
| 反応物 | 3-Phenoxyaniline | HCID 77135 | — |
| 反応物 | Ethyl acetate hexane | HCID 21226206 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | 3-Phenoxyphenylisothiocyanate | HCID 22041281 | — |
反応手順
To a stirring solution of 3-phenoxyaniline (185 mg, 1.0 mmol) in acetone (4.0 mL) at 0° C. was added thiophosgene (0.23 mL, 3.0 mmol) and the resulting reaction maintained for 30 min. The reaction determined complete by TLC (4:1 hexane/EtOAc). The reaction was concentrated, azeotroped with toluene and taken on without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07728010B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-b272333b6f17485f927833b273755ad7 |
| 出典メモ | uspto-grants-2010_06 |