化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → Ethyl 3-amino-3-phenylpropanoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Ethanol | HCID 702 | — |
| 反応物 | (3R)-3-amino-3-phenylpropanoic acid | HCID 686703 | — |
| 生成物 | Ethyl 3-amino-3-phenylpropanoate | HCID 236379 | — |
反応手順
β-Phenylalanine from II.2a (93) was suspended in ethanol (1.5 l) and the solution was saturated with gaseous HCl at room temperature. It was then heated under reflux for 4 h and stirred overnight at room temperature. The solution was cooled to 5° C. and filtered with suction. The filtrate was concentrated in vacuo, and the residue was washed with ether and dried. A white solid was obtained (yield: 52 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07220824B1 |
| 出典データセット | uspto-grants-2007_05 |
| ORD ID | ord-0ca7caf733524f749acffc30ae2cc99b |
| 出典メモ | uspto-grants-2007_05 |