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3-Bromothioanisole → 4-(3-Methylsulfanylphenyl)-3,6-dihydro-2H-pyridine-1-carboxylic Acid [4-(3-dimethylaminopyrrolidin-1-yl)phenyl]amide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Bromothioanisole | HCID 2735627 | — |
| 反応物 | 4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid [4-(3-dimethylaminopyrrolidin-1-yl)phenyl]amide | HCID 67147946 | — |
| 生成物 | 4-(3-Methylsulfanylphenyl)-3,6-dihydro-2H-pyridine-1-carboxylic Acid [4-(3-dimethylaminopyrrolidin-1-yl)phenyl]amide | HCID 58867779 | — |
反応手順
4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid [4-(3-dimethylaminopyrrolidin-1-yl)phenyl]amide was reacted with 3-bromothioanisole by method O-a. This resulted in the product with the molecular weight of 436.62 (C25H32N4OS); MS (ESI): 437 (M+H+)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07223788B2 |
| 出典データセット | uspto-grants-2007_05 |
| ORD ID | ord-20530463e29148e191de83273b8540f3 |
| 出典メモ | uspto-grants-2007_05 |