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HRID 1354751作成日：2026年10月25日

2,5-Dichlorobenzonitrile → 1-(4-Chloro-2-cyanophenyl)piperidine-4-carboxylic Acid [4-(3-dimethylaminopyrrolidin-1-yl)phenyl]amide

https://huagongshe.com/reaction/1354751

反応式

関与物質

役割名称HCID仕込み量
反応物2,5-DichlorobenzonitrileHCID 89000—
反応物Piperidine-4-carboxylic acid [4-(3-dimethylaminopyrrolidin-1-yl)phenyl]amideHCID 67147939—
生成物1-(4-Chloro-2-cyanophenyl)piperidine-4-carboxylic Acid [4-(3-dimethylaminopyrrolidin-1-yl)phenyl]amideHCID 58867765—

反応手順

Piperidine-4-carboxylic acid [4-(3-dimethylaminopyrrolidin-1-yl)phenyl]amide was reacted with 2,5-dichlorobenzonitrile as described in example 323. This resulted in the product with the molecular weight of 452.00 (C25H30ClN5O); MS (ESI): 452 (M+H+).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07223788B2
出典データセットuspto-grants-2007_05
ORD IDord-e407c0b0433a4d6a863ae630094072b8
出典メモuspto-grants-2007_05